A personal locator beacon was activated by the pair at 12.50pm (AEST) on Tuesday, March 6. RCC Australia tasked a Karratha based helicopter and local police to a creek about 73km south-east of Karratha.
Police arrived at the creek but could not drive through the flooded waters to rescue the pair whose vehicle was submerged.
The helicopter arrived and has taken the tourists to Roebourne.
Police were expecting to return to Roebourne where the pair are safe and uninjured.
AMSA urges people travelling in remote areas to carry a personal locator beacon with them in the case of an emergency, along with satellite phones.
Weather in the area resulted in flash flooding and low cloud.
RCC Australia would like to thank all involved in the rescue, including WA Police and the helicopter crew.